A 3D printer's accuracy depends on tight belts and a perfectly level bed, both of which a careless move can throw off in seconds. Homing the gantry, locking the axes, and packing it like the precision instrument it is keeps your first print looking like your last.
Pro tip: Back up your slicer profiles and any custom start G-code to a USB drive or cloud folder before the move, in case settings get reset during setup at the new place.
Watch out: Never move a 3D printer with filament still threaded through a warm nozzle; it can cool and clog the hot end before the printer even reaches the new home.